Corrected Sodium for Na 125, Glucose 800 mg/dL (HHS)
With severely low sodium of 125 mmol/L and critically high glucose of 800 mg/dL (HHS), the corrected sodium is approximately 135 mmol/L.
How to use this tool
- Enter the measured serum sodium in mmol/L.
- Enter the blood glucose in mg/dL.
- Read the glucose-corrected sodium value.
- Compare it with the reference note shown.
Assess the true sodium level in hyperosmolar hyperglycemic state (HHS) with glucose of 800 mg/dL.
Frequently asked questions
- Why does high glucose lower measured sodium?
- Glucose is osmotically active and draws water out of cells into the blood, diluting sodium. Correcting for glucose estimates the sodium that would remain once glucose normalises.
- Should I use the 1.6 or 2.4 correction factor?
- 1.6 is the traditional Katz factor used here. Some evidence supports a larger factor (about 2.4) at very high glucose, so the corrected value is an approximation.
- What units does this use?
- Glucose is entered in mg/dL (US conventional units) and sodium in mmol/L (equivalent to mEq/L), with a baseline glucose of 100 mg/dL.